Ninja Assasins talked about a ninja named Raizo (Rain), which is one of the world’s sadistic. Ozunu clan picked raizo to be trained to be a ninja assassin. This clan is a secret society whose existence is considered as a myth. Raizo escape from them and disappeared. Currently, he waited for the right time for revenge.

Mika Coretti which is the European Interpol agent find the flow of government funds to finance the suspected killer. Mika discovered the secret archives of keberanan murders that have occurred. Takeshi which is one of the clan ozunu ordered to do a murder to mica. Mika saves Raizo of his attackers, but he also knows that the clan will never stop until they were both killed. Raizo and Mika have each honest other if they want to survive and destroy the Ozunu Clan.